If DNA contained sulfur instead of phosphorus and proteins contained phosphorus instead of sulfur, what would have been the outcome of Hershey and Chase experiment?
- Radioactive phosphorus in bacterial cells
- No radioactive sulfur in bacterial cells
- Both radioactive sulfur and phosphorus in bacterial cells
- Radioactive sulfur in bacterial cells
Answer
(4) Radioactive sulfur in bacterial cells
Solution
In the Hershey–Chase experiment only the genetic material (DNA) of the bacteriophage enters the bacterium; the protein coat stays outside and is removed by blending and centrifugation.
Given case: DNA contains sulfur ⇒ DNA would be labelled with radioactive sulfur; protein contains phosphorus ⇒ protein would be labelled with radioactive phosphorus.
∴ DNA (radioactive sulfur) enters the bacterial cells, while the protein (radioactive phosphorus) remains in the supernatant.
⇒ Radioactive sulfur would be found in the bacterial cells.
Answer: (4)