A gene locus has two alleles A, a. If the frequency of dominant allele A is 0.4, then what will be the frequency of homozygous dominant, heterozygous and homozygous recessive individuals in the population?
- 0.16 (AA); 0.48 (Aa); 0.36 (aa)
- 0.16 (AA); 0.36 (Aa); 0.48 (aa)
- 0.36 (AA); 0.48 (Aa); 0.16 (aa)
- 0.16 (AA); 0.24 (Aa); 0.36 (aa)
Answer
(1) 0.16 (AA); 0.48 (Aa); 0.36 (aa)
Solution
As per the Hardy–Weinberg principle, p2 + 2pq + q2 = 1.
Given p = 0.4
q = 1 - 0.4 = 0.6
AA: p2 = (0.4)2 = 0.16
Aa: 2pq = 2 0.4 0.6 = 0.48
aa: q2 = (0.6)2 = 0.36
Answer: (1)