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Principles of Inheritance and Variation · Question 160

AIPMT 2001MCQEasy📈 Topic in 50% papers+4−1
1

Sickle cell anaemia is due to

  1. Change of amino acid in either or chain of haemoglobin
  2. Change of amino acid in chain of haemoglobin
  3. Change of amino acid in both and chain of haemoglobin
  4. Change of amino acid in chain of haemoglobin

Answer

(4) Change of amino acid in chain of haemoglobin

Solution

As per NCERT, sickle-cell anaemia is caused by the substitution of glutamic acid (Glu) by valine (Val) at the sixth position of the globin chain of haemoglobin.

⇒ This results from a single base substitution (GAG → GUG) in the globin gene.

Answer: (4)

AIPMT 2001

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2

Number of Barr bodies in XXXX female is

  1. 3
  2. 1
  3. 2
  4. 4
AIPMT 2001
3

Male XX and female XY sometime occur due to

  1. Aneuploidy
  2. Deletion
  3. Transfer of segments in X and Y chromosomes
  4. Hormonal imbalance
AIPMT 2001
4

Probability of four sons to a couple is : -

  1. 116
  2. 18
  3. 14
  4. 132
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5

Due to the cross between TTRr × ttrr the resultant progenies showed how many percent plants tall, red flowered:

  1. 50%
  2. 100%
  3. 75%
  4. 25%
AIPMT 2000
6

According to mendelism which character is showing dominance?

  1. Green colour in seed coat
  2. Wrinkled seed
  3. Terminal position of flower
  4. Green pod colour
AIPMT 2000
7

Mongolian idiots are due to trisomy in 21st chromosome is called:

  1. Klinefelter's syndrome
  2. Down's syndrome
  3. Turner's syndrome
  4. Triplex syndrome
AIPMT 2000
8

Erythroblastosis foetalis is caused when:

  1. Rh- female & Rh+ male
  2. Rh- female & Rh- male
  3. Rh+ female & Rh+ male
  4. Rh+ female & Rh- male
AIPMT 2000
9

In Drosophila the XXY condition leads to femaleness whereas in human beings the same condition leads to Klinefelter's syndrome in male. It proves:

  1. Y chromosome is active in sex determination in both human beings and Drosophila
  2. In Drosophila Y-chromosome decides femaleness
  3. Y chromosome of man have genes for syndrome
  4. In human beings Y chromosome is active in sex determination
AIPMT 2000

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