Which functional group participates in disulphide bond formation in proteins?
- Thioester
- Thioether
- Thiol
- Thiolactone
Answer
(3) Thiol
Solution
Disulphide bonds (-S-S-) are formed between the side chains of two cysteine residues.
The thiol (-SH) groups of the two cysteine units are oxidised: R-SH + HS-R' [O] R-S-S-R' + H2O
As per NCERT, the tertiary structure of proteins is stabilised by hydrogen bonds, disulphide linkages, van der Waals and electrostatic forces of attraction.
Answer: (3)