Inhibition of Succinic dehydrogenase enzyme by malonate is a classical example of:
- Cofactor inhibition
- Feedback inhibition
- Competitive inhibition
- Enzyme activation
Answer
(3) Competitive inhibition
Solution
Malonate closely resembles the substrate succinate in structure. It competes with succinate for the active site of succinic dehydrogenase and blocks it, so the inhibition is competitive inhibition.
Answer: (3)