Given below are two statements: In the light of the above statements, choose the correct answer from the options given below :
- Statement I is incorrect but Statement II is correct
- Both Statement I and Statement II are correct
- Both Statement I and Statement II are incorrect
- Statement I is correct but Statement II is incorrect
Answer
(1) Statement I is incorrect but Statement II is correct
Solution
Statement I: Incorrect – as per NCERT, sickle-cell anaemia is an autosomal recessive trait, while haemophilia is a sex-linked (X-linked) recessive disease.
Statement II: Correct – both are blood disorders: in sickle-cell anaemia the RBCs become sickle-shaped due to a defective haemoglobin (Glu → Val at the sixth position of the β-globin chain), and in haemophilia a protein of the blood-clotting cascade is affected, so blood does not clot normally.
Answer: (1)