Which of the following statements are correct with reference to packaging of DNA helix ? Choose the correct answer from the options given below :
- B, D and E only
- A, B and D only
- C, D and E only
- A, C and E only
Answer
(4) A, C and E only
Solution
As per NCERT, histones are positively charged basic proteins, rich in the basic amino acid residues lysine and arginine.
⇒ Eight histone molecules form a histone octamer ⇒ A and C are correct; B is incorrect.
∵ DNA is negatively charged (phosphate groups), the negatively charged DNA is wrapped around the positively charged histone octamer to form a nucleosome ⇒ D is incorrect.
As per NCERT, packaging of chromatin at higher levels requires an additional set of proteins called non-histone chromosomal (NHC) proteins ⇒ E is correct.
∴ Correct statements: A, C and E only.
Answer: (4)