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Biotechnology and its Applications · Question 61

AIPMT 2009MCQMedium📈 Topic in 12% papers+4−1
1

The genetic defect – adenosine deaminase (ADA) deficiency may be cured permanently by

  1. Introducing bone marrow cells producing ADA into cells at early embryonic stages
  2. Periodic infusion of genetically engineered lymphocytes having functional ADA cDNA
  3. Administering adenosine deaminase activators
  4. Enzyme replacement therapy

Answer

(1) Introducing bone marrow cells producing ADA into cells at early embryonic stages

Solution

As per NCERT, ADA deficiency can be treated by bone marrow transplantation, enzyme replacement therapy or periodic infusion of genetically engineered lymphocytes — none of these is completely curative, as the lymphocytes are not immortal.

⇒ NCERT states: if the gene isolated from bone marrow cells producing ADA is introduced into cells at early embryonic stages, it could be a permanent cure.

Answer: (1)

AIPMT 2009

Keep practising — Biotechnology and its Applications

2

What is true about Bt toxin?

  1. The activated toxin enters the ovaries of the pest to sterilise it and thus prevent its multiplication.
  2. Bt protein exists as active toxin in the Bacillus
  3. The concerned Bacillus has antitoxins
  4. The inactive protoxin gets converted into active form in the insect gut
AIPMT 2009
3

Transgenic plants are the ones -

  1. Produced after protoplast fusion in artificial medium
  2. Produced by a somatic embryo in artificial medium
  3. Generated by introducing foreign DNA into a cell and regenerating a plant from that cell
  4. Grown in artificial medium after hybridization in the field
AIPMT 2009
4

What is antisense technology?

  1. RNA polymerase producing DNA
  2. Production of somaclonal variants in tissue cultures
  3. When a piece of RNA that is complementary in sequence is used to stop expression of a specific gene
  4. A cell displaying a foreign antigen used for synthesis of antigens
AIPMT 2009
5

Cry I endotoxins obtained from Bacillus thuringiensis are effective against:

  1. Mosquitoes
  2. Flies
  3. Nematodes
  4. Boll worms
AIPMT 2008
6

Main objective of production/use of herbicide resistant GM crops is to:

  1. eliminate weeds from the field without the use of manual labour
  2. eliminate weeds from the field without the use of herbicides
  3. encourage eco-friendly herbicides
  4. reduce herbicide accumulation in food articles for health safety
AIPMT 2008
7

Human insulin is being commercially produced from a transgenic species of:

  1. Escherichia
  2. Mycobacterium
  3. Rhizobium
  4. Saccharomyces
AIPMT 2008
8

A transgenic food crop which may help in solving the problem of night blindness in developing countries is

  1. Flavr Savr tomatoes
  2. Bt soybean
  3. Starlink maize
  4. Golden rice
AIPMT 2008
9

Golden rice is a promising transgenic crop. When released for cultivation, it will help in

  1. Herbicide tolerance
  2. Alleviation of vitamin A deficiency
  3. Producing a petrol-like fuel from rice
  4. Pest resistance
AIPMT 2006
10

Bacillus thuringiensis (Bt) strains have been used for designing novel -

  1. Bio-metallurgical techniques
  2. Biofertilizers
  3. Bioinsecticidal plants
  4. Bio-mineralization processes
AIPMT 2005
11

Golden rice is a transgenic crop of the future with the following improved trait -

  1. High lysine (essential amino acid) content
  2. High protein content
  3. Insect resistance
  4. High vitamin A content
AIPMT 2005

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