Which of the following is a correct match -
- Sickle cell anaemia = X – Chromosome
- Down Syndrome = 21st Chromosome
- Haemophilia = Y – Chromosome
- Parkinson Disease = X & Y Chromosome
Answer
(2) Down Syndrome = 21st Chromosome
Solution
As per NCERT, Down's syndrome is caused by the presence of an additional copy of chromosome number 21 (trisomy of 21).
Sickle cell anaemia is an autosomal (not X-linked) recessive disorder.
Haemophilia is a sex-linked recessive disorder whose gene lies on the X-chromosome, not on the Y-chromosome.
Parkinson disease is not a sex-chromosome disorder.
∴ The correct match is Down Syndrome = 21st chromosome.
Answer: (2)