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Molecular Basis of Inheritance · Question 62

NEET (UG) 2019MCQMedium📈 Topic in 25% papers+4−1
1

Under which of the following conditions will there be no change in the reading frame of following mRNA? 5' AACAGCGGUGCUAUU 3'

  1. Insertion of A and G at 4th and 5th positions respectively
  2. Deletion of GGU from 7th, 8th and 9th positions
  3. Insertion of G at 5th position
  4. Deletion of G from 5th position

Answer

(2) Deletion of GGU from 7th, 8th and 9th positions

Solution

The codons are read in triplets without punctuation:

5' AAC AGC GGU GCU AUU 3'

Bases 7, 8 and 9 form the third codon GGU.

Deleting these three bases removes one whole codon:

5' AAC AGC GCU AUU 3' — the remaining codons are read unchanged.

As per NCERT, insertion or deletion of one or two bases changes the reading frame from the point of change (frameshift), whereas insertion or deletion of three bases (or multiples of three) inserts or deletes one or more codons and the reading frame from that point remains unaltered.

Options (1), (3) and (4) (one or two bases) cause frameshifts.

Answer: (2)

NEET (UG) 2019

Keep practising — Molecular Basis of Inheritance

2

Which of the following features of genetic code does allow bacteria to produce human insulin by recombinant DNA technology?

  1. Genetic code is nearly universal
  2. Genetic code is specific
  3. Genetic code is not ambiguous
  4. Genetic code is redundant
NEET (UG) 2019
3

Match the following genes of the Lac operon with their respective products : Select the correct option.

  1. (a)-(iii), (b)-(i), (c)-(iv), (d)-(ii)
  2. (a)-(iii), (b)-(iv), (c)-(i), (d)-(ii)
  3. (a)-(i), (b)-(iii), (c)-(ii), (d)-(iv)
  4. (a)-(iii), (b)-(i), (c)-(ii), (d)-(iv)
NEET (UG) 2019
4

The experimental proof for semi-conservative replication of DNA was first shown in a

  1. fungus
  2. bacterium
  3. plant
  4. virus
NEET 2018
5

Select the correct match :

  1. Alec Jeffreys - Streptococcus pneumoniae
  2. Alfred Hershey and Martha Chase - TMV
  3. Matthew Meselson and F. Stahl - Pisum sativum
  4. Francois Jacob and Jacques Monod - Lac operon
NEET 2018
6

Select the correct match :

  1. Ribozyme - Nucleic acid
  2. F2 Recessive parent - Dihybrid cross
  3. T.H. Morgan - Transduction
  4. G. Mendel - Transformation
NEET 2018
7

Many ribosomes may associate with a single mRNA to form multiple copies of a polypeptide simultaneously. Such strings of ribosomes are termed as

  1. polysome
  2. polyhedral bodies
  3. plastidome
  4. nucleosome
NEET 2018
8

AGGTATCGCAT is a sequence from the coding strand of a gene. What will be the corresponding sequence of the transcribed mRNA?

  1. AGGUAUCGCAU
  2. UGGTUTCGCAT
  3. ACCUAUGCGAU
  4. UCCAUAGCGUA
NEET 2018
9

All of the following are part of an operon except

  1. an operator
  2. structural genes
  3. an enhancer
  4. a promoter
NEET 2018
10

The final proof for DNA as the genetic material came from the experiments of

  1. Griffith
  2. Hargobind Khorana
  3. Avery, MacLeod and McCarty
  4. Hershey and Chase
NEET 2017
11

If there are 999 bases in an RNA that codes for a protein with 333 amino acids, and the base at position 901 is deleted such that the length of the RNA becomes 998 bases, how many codons will be altered ?

  1. 1
  2. 11
  3. 333
  4. 33
NEET 2017

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