Which one of the following pairs correctly matches a hormone with a disease resulting from its deficiency?
- Relaxin – Gigantism
- Prolactin – Cretinism
- Parathyroid hormone – Tetany
- Insulin – Diabetes insipidus
Answer
(3) Parathyroid hormone – Tetany
Solution
(1) Gigantism is due to excess growth hormone, not relaxin deficiency.
(2) Cretinism is due to deficiency of thyroid hormones (hypothyroidism in childhood), not prolactin.
(3) Parathyroid hormone (PTH) raises blood Ca2+; its deficiency lowers blood calcium ⇒ muscle spasms, i.e. tetany.
(4) Diabetes insipidus is due to deficiency of ADH (vasopressin); insulin deficiency causes diabetes mellitus.
∴ Parathyroid hormone – Tetany is the correct pair.
Answer: (3)