The sixth mutant codon of beta globin gene causing polymerization of Haemoglobin and change in RBC shape is .
- CAG
- AUG
- GUG
- GAG
Answer
(3) GUG
Solution
In sickle-cell anaemia glutamic acid at the sixth position of the β-globin chain is replaced by valine.
This is due to the single base change GAG → GUG.
So the mutant codon is GUG.
Answer: (3)