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Biotechnology and its Applications · Question 58

AIPMT 2010 (Prelims)MCQEasy📈 Topic in 25% papers+4−1
1

Genetic engineering has been successfully used for producing –

  1. transgenic models for studying new treatments for certain cardiac disease
  2. animals like bulls for farm work as they have super power
  3. transgenic mice for testing safety of polio vaccine before use in humans
  4. transgenic Cow-Rosie which produces high fat milk for making ghee

Answer

(3) transgenic mice for testing safety of polio vaccine before use in humans

Solution

As per NCERT, transgenic mice are being developed for use in testing the safety of vaccines before they are used on humans; transgenic mice are being used to test the safety of the polio vaccine. (3) is correct.

(1) Incorrect: NCERT lists transgenic models for cancer, cystic fibrosis, rheumatoid arthritis and Alzheimer's disease.

(2) Incorrect: no such transgenic bulls exist.

(4) Incorrect: Rosie, the first transgenic cow (1997), produced human protein-enriched milk (2.4 g per litre) containing human -lactalbumin, not high-fat milk.

Answer: (3)

AIPMT 2010 (Prelims)

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2

Some of the characteristics of Bt cotton are –

  1. High yield and production of toxic protein crystals which kill dipteran pests
  2. High yield and resistance to bollworms
  3. Long fibre and resistance to aphids
  4. Medium yield, long fibre and resistance to beetle pests
AIPMT 2010 (Prelims)
3

An improved variety of transgenic basmati rice

  1. gives high yield but has no characteristic aroma
  2. does not require chemical fertilizers and growth hormones
  3. is completely resistant to all insect pests and diseases of paddy
  4. gives high yield and is rich in vitamin A
AIPMT 2010 (Prelims)
4

The genetic defect – adenosine deaminase (ADA) deficiency may be cured permanently by

  1. Introducing bone marrow cells producing ADA into cells at early embryonic stages
  2. Periodic infusion of genetically engineered lymphocytes having functional ADA cDNA
  3. Administering adenosine deaminase activators
  4. Enzyme replacement therapy
AIPMT 2009
5

What is true about Bt toxin?

  1. The activated toxin enters the ovaries of the pest to sterilise it and thus prevent its multiplication.
  2. Bt protein exists as active toxin in the Bacillus
  3. The concerned Bacillus has antitoxins
  4. The inactive protoxin gets converted into active form in the insect gut
AIPMT 2009
6

Transgenic plants are the ones -

  1. Produced after protoplast fusion in artificial medium
  2. Produced by a somatic embryo in artificial medium
  3. Generated by introducing foreign DNA into a cell and regenerating a plant from that cell
  4. Grown in artificial medium after hybridization in the field
AIPMT 2009
7

What is antisense technology?

  1. RNA polymerase producing DNA
  2. Production of somaclonal variants in tissue cultures
  3. When a piece of RNA that is complementary in sequence is used to stop expression of a specific gene
  4. A cell displaying a foreign antigen used for synthesis of antigens
AIPMT 2009
8

Cry I endotoxins obtained from Bacillus thuringiensis are effective against:

  1. Mosquitoes
  2. Flies
  3. Nematodes
  4. Boll worms
AIPMT 2008
9

Main objective of production/use of herbicide resistant GM crops is to:

  1. eliminate weeds from the field without the use of manual labour
  2. eliminate weeds from the field without the use of herbicides
  3. encourage eco-friendly herbicides
  4. reduce herbicide accumulation in food articles for health safety
AIPMT 2008
10

Human insulin is being commercially produced from a transgenic species of:

  1. Escherichia
  2. Mycobacterium
  3. Rhizobium
  4. Saccharomyces
AIPMT 2008
11

A transgenic food crop which may help in solving the problem of night blindness in developing countries is

  1. Flavr Savr tomatoes
  2. Bt soybean
  3. Starlink maize
  4. Golden rice
AIPMT 2008

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