How does steroid hormone influence the cellular activities?
- Activating cyclic AMP located on the cell membrane
- Using aquaporin channels as second messenger
- Changing the permeability of the cell membrane
- Binding to DNA and forming a gene-hormone complex
Answer
(4) Binding to DNA and forming a gene-hormone complex
Solution
Steroid hormones are lipid soluble, so they cross the cell membrane and bind to intracellular (nuclear) receptors.
⇒ As per NCERT, hormones which interact with intracellular receptors (e.g., steroid hormones, iodothyronines) mostly regulate gene expression or chromosome function by the interaction of the hormone-receptor complex with the genome.
∵ cAMP as second messenger is used by protein (membrane-receptor) hormones,
∴ steroid hormones act by binding to DNA and forming a gene-hormone complex.
Answer: (4)