Which of the following glucose transporters is insulin-dependent?
- GLUT III
- GLUT IV
- GLUT I
- GLUT II
Answer
(2) GLUT IV
Solution
Glucose enters cells by facilitated diffusion through glucose transporters (GLUT).
• GLUT I and GLUT III – basal glucose uptake (RBCs, brain); insulin-independent
• GLUT II – liver, pancreatic β-cells, kidney; insulin-independent
• GLUT IV – skeletal muscle, heart muscle and adipose tissue; insulin stimulates the movement of GLUT IV to the cell membrane
∴ GLUT IV is the insulin-dependent glucose transporter.
Answer: (2)