Which of the following cannot be detected in a developing foetus by amniocentesis ?
- Sex of the foetus
- jaundice
- Klinefelter syndrome
- Down syndrome
Answer
(2) jaundice
Solution
Amniocentesis is a foetal sex determination test based on the chromosomal pattern of foetal cells present in the amniotic fluid surrounding the developing embryo.
⇒ By studying the karyotype of these cells, sex of the foetus and chromosomal disorders such as Down syndrome (trisomy 21) and Klinefelter syndrome (XXY) can be detected.
∵ Jaundice is not a chromosomal abnormality (it is due to excess bilirubin, usually appearing after birth), it cannot be detected by amniocentesis.
Answer: (2)