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Principles of Inheritance and Variation · Question 114

AIPMT 2006MCQEasy📈 Topic in 50% papers+4−1
1

Both sickle cell anemia and Huntington's chorea are-

  1. Congenital disorders
  2. Bacteria-related diseases
  3. Virus-related diseases
  4. Pollutant-induced disorders

Answer

(1) Congenital disorders

Solution

∵ Sickle-cell anaemia is an autosomal recessive Mendelian disorder caused by a point mutation (GAG → GUG) in the β-globin gene.

∵ Huntington's chorea is an autosomal dominant Mendelian disorder.

⇒ Both are inherited through genes from the parents and are present from birth (genetic, i.e. congenital); neither is caused by bacteria, viruses or pollutants.

∴ Both are congenital disorders.

Answer: (1)

AIPMT 2006

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2

Test cross involves-

  1. Crossing between two F1 hybrids
  2. Crossing the F1 hybrid with a double recessive genotype
  3. Crossing between two genotypes with recessive trait
  4. Crossing between two genotypes with dominant trait
AIPMT 2006
3

If a colour blind woman marries a normal visioned man, their sons will be

  1. All normal visioned
  2. Three-fourths colourblind and one-fourth normal
  3. One-half colourblind and one-half normal
  4. All colourblind
AIPMT 2006
4

Cri-du-chat syndrome in humans is caused by the-

  1. Loss of half of the long arm of chromosome 5
  2. Loss of half of the short arm of chromosome 5
  3. Trisomy of 21st chromosome
  4. Fertilization of an XX egg by a normal Y-bearing sperm
AIPMT 2006
5

Sickle cell anaemia has not been eliminated from the African population because-

  1. It is not a fatal disease
  2. It is controlled by dominant genes
  3. It is controlled by recessive genes
  4. It provides immunity against malaria
AIPMT 2006
6

In Mendel's experiments with garden pea, round seed shape (RR) was dominant over wrinkled seeds (rr), yellow cotyledon (YY) was dominant over green cotyledon (yy). What are the expected phenotypes in the F2 generation of the cross RRYY × rryy?

  1. Round seeds with yellow cotyledons, and wrinkled seeds with yellow cotyledons
  2. Only wrinkled seeds with green cotyledons
  3. Only wrinkled seeds with yellow cotyledons
  4. Only round seeds with green cotyledons
AIPMT 2006
7

How many different kinds of gametes will be produced by a plant having the genotype AABbCC?

  1. Two
  2. Nine
  3. Four
  4. Three
AIPMT 2006
8

Phenotype of an organism is the result of-

  1. Environmental changes and sexual dimorphism
  2. Cytoplasmic effects and nutrition
  3. Genotype and environment interactions
  4. Mutations and linkages
AIPMT 2006
9

Which one of the following is an example of polygenic inheritance?

  1. Skin colour in humans
  2. Pod shape in garden pea
  3. Production of male honey bee
  4. Flower colour in Mirabilis jalapa
AIPMT 2006
10

In order to find out the different types of gametes produced by a pea plant having the genotype AaBb, it should be crossed to a plant with the genotype -

  1. aaBB
  2. aabb
  3. AaBb
  4. AABB
AIPMT 2005
11

G-6-P dehydrogenase deficiency is associated with haemolysis of -

  1. RBCs
  2. Lymphocytes
  3. Platelets
  4. Leucocytes
AIPMT 2005

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