In higher vertebrates, the immune system can distinguish self-cells and non-self. If this property is lost due to genetic abnormality and it attacks self-cells, then it leads to
- Active immunity
- Allergic response
- Graft rejection
- Auto-immune disease
Answer
(4) Auto-immune disease
Solution
As per NCERT, the immune system of higher vertebrates can distinguish foreign molecules as well as foreign organisms (non-self) from self-cells.
∵ When, due to genetic or other unknown reasons, the body attacks its own self-cells, the result is damage to the body.
∴ This is called auto-immune disease, e.g. rheumatoid arthritis.
Answer: (4)