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Principles of Inheritance and Variation · Question 137

AIPMT 2004MCQMedium📈 Topic in 0% papers+4−1
1

After a mutation at a genetic locus the character of an organism changes due to the change in :-

  1. Protein synthesis pattern
  2. RNA transcription pattern
  3. DNA replication
  4. Protein structure

Answer

(4) Protein structure

Solution

A mutation changes the base sequence of DNA at that locus.

⇒ The changed DNA is transcribed into an altered mRNA, which changes the codons and hence the sequence of amino acids in the polypeptide.

⇒ The altered amino acid sequence changes the structure (and function) of the protein, e.g. in sickle-cell anaemia Glu → Val at the sixth position of the β-globin chain.

∴ The character (phenotype) changes due to the change in protein structure.

Answer: (4)

AIPMT 2004

Keep practising — Principles of Inheritance and Variation

2

In a mutational event, when adenine is replaced by guanine, it is a case of -

  1. Frameshift mutation
  2. Transition
  3. Transversion
  4. Transcription
AIPMT 2004
3

Which one of the following traits of garden pea studied by Mendel was a recessive feature?

  1. Green seed colour
  2. Green pod colour
  3. Axial flower position
  4. Round seed shape
AIPMT 2003
4

The genes controlling the seven pea characters studied by Mendel are now known to be located on how many different chromosomes?

  1. Six
  2. Seven
  3. Five
  4. Four
AIPMT 2003
5

Two crosses between the same pair of genotypes or phenotypes in which the sources of the gametes are reversed in one cross, is known as:

  1. Reciprocal cross
  2. Reverse cross
  3. Test cross
  4. Dihybrid cross
AIPMT 2003
6

Pattern baldness, moustaches and beard in human males are examples of:

  1. Sex limited traits
  2. Sex influenced traits
  3. Sex determining traits
  4. Sex linked traits
AIPMT 2003
7

Which one of the following conditions though harmful in itself, is also a potential saviour from a mosquito borne infectious disease?

  1. Pernicious anaemia
  2. Thalassaemia
  3. Leukemia
  4. Sickle cell anaemia
AIPMT 2003
8

Down's syndrome is caused by an extra copy of chromosome number 21. What percentage of offspring produced by an affected mother and a normal father would be affected by this disorder?

  1. 50%
  2. 100%
  3. 75%
  4. 25%
AIPMT 2003
9

In Drosophila, the sex is determined by:

  1. X and Y chromosomes
  2. Whether the egg is fertilized or develops parthenogenetically
  3. The ratio of number of X-chromosomes to the sets of autosomes
  4. The ratio of pairs of X-chromosomes to the pairs of autosomes
AIPMT 2003
10

Christmas disease is another name for :-

  1. Hepatitis B
  2. Sleeping sickness
  3. Haemophilia B
  4. Down's syndrome
AIPMT 2003
11

Which of the following is the example of pleiotropy ?

  1. Thalassemia
  2. Haemophilia
  3. Sickle cell anaemia
  4. Colour blindness
AIPMT 2002

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