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Principles of Inheritance and Variation · Question 146

AIPMT 2003MCQEasy📈 Topic in 50% papers+4−1
1

Christmas disease is another name for :-

  1. Hepatitis B
  2. Sleeping sickness
  3. Haemophilia B
  4. Down's syndrome

Answer

(3) Haemophilia B

Solution

Haemophilia is a sex-linked recessive disease in which a protein involved in the cascade of blood clotting is affected.

⇒ Haemophilia A is due to deficiency of clotting factor VIII; haemophilia B is due to deficiency of clotting factor IX.

⇒ Haemophilia B was first described in a patient named Stephen Christmas, hence it is called Christmas disease.

Answer: (3)

AIPMT 2003

Keep practising — Principles of Inheritance and Variation

2

Which of the following is the example of pleiotropy ?

  1. Thalassemia
  2. Haemophilia
  3. Sickle cell anaemia
  4. Colour blindness
AIPMT 2002
3

There are three genes a, b and c. The percentage of crossing over between a and b is 20%, b and c is 28% and a and c is 8%. What is the sequence of genes on chromosome?

  1. a, b, c
  2. b, a, c
  3. a, c, b
  4. None
AIPMT 2002
4

On selfing a plant of F1 generation with genotype “AABbCC”, the phenotypic ratio in F2 generation will be

  1. 1 : 1
  2. 3 : 1
  3. 9 : 3 : 3 : 1
  4. 27 : 9 : 9 : 9 : 3 : 3 : 3 : 1
AIPMT 2002
5

A gene is said to be dominant if : -

  1. It is expressed only in heterozygous condition
  2. It expresses its effect only in homozygous stage
  3. It is never expressed in any condition
  4. It is expressed both in homozygous and heterozygous condition
AIPMT 2002
6

A diseased man marries a normal woman. They get three daughters and five sons. All the daughters were diseased and sons were normal. The gene of this disease is : -

  1. Sex linked dominant
  2. Autosomal dominant
  3. Sex linked recessive
  4. Sex limited character
AIPMT 2002
7

Which of the following is a correct match -

  1. Sickle cell anaemia = X – Chromosome
  2. Down Syndrome = 21st Chromosome
  3. Haemophilia = Y – Chromosome
  4. Parkinson Disease = X & Y Chromosome
AIPMT 2002
8

Change in sequence of nucleotide in DNA is called as -

  1. Recombination
  2. Mutation
  3. Mutagen
  4. Translation
AIPMT 2002
9

If a diploid cell is treated with colchicine then it becomes : -

  1. Tetraploid
  2. Monoploid
  3. Diploid
  4. Triploid
AIPMT 2002
10

Two non-allelic genes produce the new phenotype when present together but fail to do so independently then it is called

  1. Polygene
  2. Complementary gene
  3. Non-complementary gene
  4. Epistasis
AIPMT 2001
11

A and B genes are linked. What shall be genotype of progeny in a cross between AB/ab and ab/ab?

  1. AABB and aabb
  2. None
  3. AaBb and aabb
  4. AAbb and aabb
AIPMT 2001

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