Toxic agents present in food which interfere with thyroxine synthesis lead to the development of
- toxic goitre
- cretinism
- simple goitre
- thyrotoxicosis
Answer
(3) simple goitre
Solution
Substances in food that interfere with thyroxine synthesis (goitrogens) lower the level of thyroid hormones in blood, just like iodine deficiency.
⇒ Low thyroxine increases TSH secretion from the anterior pituitary, which causes enlargement of the thyroid gland.
⇒ As per NCERT, this hypothyroidism and enlargement of the thyroid gland is called goitre (simple goitre).
⇒ Toxic goitre and thyrotoxicosis are due to excess thyroxine; cretinism results from hypothyroidism during foetal life or infancy.
Answer: (3)