Represented below is the inheritance pattern of a certain type of traits in humans. Which one of the following conditions could be an example of this pattern ? [figure]
- Haemophilia
- Sickle cell anaemia
- Thalassemia
- Phenylketonuria
Answer
(1) Haemophilia
Solution
The figure shows criss-cross inheritance: the trait passes from mother to son and from father to daughter.
∵ A son receives his X chromosome only from the mother, and a daughter receives the father's X chromosome ⇒ this is the pattern of an X-linked recessive trait.
As per NCERT, haemophilia is a sex-linked recessive disease (gene on the X chromosome), transmitted from an unaffected carrier female to some of the male progeny.
Sickle cell anaemia, thalassemia and phenylketonuria are autosomal recessive disorders.
∴ Haemophilia fits the given pattern.
Answer: (1)