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Molecular Basis of Inheritance · Question 127

AIPMT 2006MCQEasy📈 Topic in 25% papers+4−1
1

One gene-one enzyme hypothesis was postulated by -

  1. A. Garrod
  2. Hershey and Chase
  3. Beadle and Tatum
  4. R. Franklin

Answer

(3) Beadle and Tatum

Solution

∵ G. W. Beadle and E. L. Tatum (1941), working on the mould Neurospora crassa, showed that each gene controls the synthesis of one specific enzyme.

⇒ Garrod studied inborn errors of metabolism; Hershey and Chase proved DNA is the genetic material; Rosalind Franklin produced X-ray diffraction data of DNA.

∴ The one gene–one enzyme hypothesis was postulated by Beadle and Tatum.

Answer: (3)

AIPMT 2006

Keep practising — Molecular Basis of Inheritance

2

Antiparallel strands of a DNA molecule means that-

  1. The phosphate groups at the start of two DNA strands are in opposite position (pole)
  2. One strand turns anti-clockwise
  3. One strand turns clockwise
  4. The phosphate groups of two DNA strands, at their ends, share the same position
AIPMT 2006
3

Which antibiotic inhibits interaction between tRNA and mRNA during bacterial protein synthesis?

  1. Neomycin
  2. Erythromycin
  3. Tetracycline
  4. Streptomycin
AIPMT 2006
4

Amino acid sequence, in protein synthesis is decided by the sequence of -

  1. cDNA
  2. mRNA
  3. tRNA
  4. rRNA
AIPMT 2006
5

E. coli cells with a mutated z gene of the lac operon cannot grow in medium containing only lactose as the source of energy because -

  1. They cannot transport lactose from the medium into the cell
  2. They cannot synthesize functional -galactosidase
  3. In the presence of glucose, E. coli cells do not utilize lactose
  4. The lac operon is constitutively active in these cells
AIPMT 2005
6

Telomerase is an enzyme which is a -

  1. RNA
  2. Repetitive DNA
  3. Simple protein
  4. Ribonucleoprotein
AIPMT 2005
7

Protein synthesis in an animal cell occurs -

  1. On ribosomes present in the nucleolus as well as in cytoplasm
  2. On ribosomes present in cytoplasm as well as in mitochondria
  3. Only on the ribosomes present in cytosol
  4. Only on ribosomes attached to the nuclear envelope and endoplasmic reticulum
AIPMT 2005
8

Which one of the following makes use of RNA as a template to synthesize DNA -

  1. Reverse transcriptase
  2. DNA dependent RNA polymerase
  3. RNA polymerase
  4. DNA polymerase
AIPMT 2005
9

During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at the point. What is the sequence called?

  1. TATA box
  2. GGTT box
  3. CAAT box
  4. AAAT box
AIPMT 2005
10

Production of a human protein in bacteria by genetic engineering is possible because

  1. The human chromosome can replicate in bacterial cell
  2. The genetic code is universal
  3. Bacterial cell can carry out the RNA splicing reactions
  4. The mechanism of gene regulation is identical in humans and bacteria
AIPMT 2005
11

During replication of a bacterial chromosome DNA synthesis starts from a replication origin site and

  1. RNA primers are involved
  2. is facilitated by telomerase
  3. moves in one direction of the site
  4. moves in bi-directional way
AIPMT 2004

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