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Biotechnology and its Applications · Question 48

AIPMT 2012 (Mains)MCQEasy📈 Topic in 12% papers+4−1
1

The first clinical gene therapy was given for treating

  1. Rheumatoid arthritis
  2. Adenosine deaminase deficiency
  3. Diabetes mellitus
  4. Chicken pox

Answer

(2) Adenosine deaminase deficiency

Solution

As per NCERT, the first clinical gene therapy was given in 1990 to a 4-year-old girl with adenosine deaminase (ADA) deficiency.

Lymphocytes from her blood were grown in culture, a functional ADA cDNA was introduced using a retroviral vector, and the cells were returned to the patient.

Answer: (2)

AIPMT 2012 (Mains)

Keep practising — Biotechnology and its Applications

2

A single strand of nucleic acid tagged with a radioactive molecule is called

  1. Probe
  2. Selectable marker
  3. Vector
  4. Plasmid
AIPMT 2012 (Prelims)
3

Consumption of which one of the following foods can prevent the kind of blindness associated with vitamin 'A' deficiency?

  1. Flavr Savr tomato
  2. Canola
  3. Bt-brinjal
  4. Golden rice
AIPMT 2012 (Prelims)
4

Bacillus thuringiensis forms protein crystals which contain insecticidal protein. This protein:

  1. is activated by acid pH of the foregut of the insect pest.
  2. binds with epithelial cells of midgut of the insect pest ultimately killing it
  3. is coded by several genes including the gene cry
  4. does not kill the carrier bacterium which is itself resistant to this toxin
AIPMT 2011 (Mains)
5

Silencing of mRNA has been used in producing transgenic plants resistant to:

  1. White rusts
  2. Nematodes
  3. Bacterial blights
  4. Bollworms
AIPMT 2011 (Mains)
6

Maximum number of existing transgenic animals is of :

  1. Mice
  2. Cow
  3. Pig
  4. Fish
AIPMT 2011 (Prelims)
7

The process of RNA interference has been used in the development of plants resistant to :

  1. Nematodes
  2. Fungi
  3. Viruses
  4. Insects
AIPMT 2011 (Prelims)
8

Which one of the following is now being commercially produced by biotechnological procedures?

  1. Insulin
  2. Morphine
  3. Nicotine
  4. Quinine
AIPMT 2010 (Mains)
9

DNA or RNA segment tagged with a radioactive molecule is called –

  1. Clone
  2. Probe
  3. Plasmid
  4. Vector
AIPMT 2010 (Prelims)
10

The genetically-modified (GM) brinjal in India has been developed for:

  1. Enhancing shelf life
  2. Insect-resistance
  3. Drought-resistance
  4. Enhancing mineral content
AIPMT 2010 (Prelims)
11

Genetic engineering has been successfully used for producing –

  1. transgenic models for studying new treatments for certain cardiac disease
  2. animals like bulls for farm work as they have super power
  3. transgenic mice for testing safety of polio vaccine before use in humans
  4. transgenic Cow-Rosie which produces high fat milk for making ghee
AIPMT 2010 (Prelims)

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