A woman with normal vision, but whose father was colour blind, marries a colour blind man. Suppose that the fourth child of this couple was a boy. This boy -
- May be colour blind or may have normal vision
- Must have normal colour vision
- Must be colour blind
- Will be partially colour blind since he is heterozygous for the colour blind mutant allele.
Answer
(1) May be colour blind or may have normal vision
Solution
∵ Her father was colour blind ( XcY) ⇒ the woman with normal vision is a carrier: XCXc.
⇒ Husband is colour blind: XcY.
⇒ A son gets his Y from the father and one X from the mother: XCY (normal) or XcY (colour blind), each with probability 12.
∴ Every son, whatever his birth order, may be colour blind or may have normal vision. (A male is hemizygous, so he can never be heterozygous.)
Answer: (1)