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Biotechnology and its Applications · Question 45

NEET 2013 (Karnataka)MCQEasy📈 Topic in 75% papers+4−1
1

RNA interference involves :-

  1. Interference of RNA in synthesis of DNA
  2. Synthesis of cDNA from RNA using reverse transcriptase
  3. Synthesis of mRNA from DNA
  4. Silencing of specific mRNA due to complementary RNA

Answer

(4) Silencing of specific mRNA due to complementary RNA

Solution

As per NCERT, RNA interference (RNAi) takes place in all eukaryotic organisms as a method of cellular defence.

⇒ It involves silencing of a specific mRNA due to a complementary dsRNA molecule that binds to and prevents translation of the mRNA.

⇒ Example: nematode-specific genes introduced into tobacco produce sense and anti-sense RNA, which silence the mRNA of Meloidogyne incognita.

Answer: (4)

NEET 2013 (Karnataka)

Keep practising — Biotechnology and its Applications

2

Which one of the following vectors is used to replace the defective gene in gene therapy ?

  1. Ti plasmid
  2. Cosmid
  3. Ri plasmid
  4. Adenovirus
NEET 2013 (Karnataka)
3

Tobacco plants resistant to a nematode have been developed by the introduction of DNA that produced (in the host cells) :

  1. An antifeedant
  2. A toxic protein
  3. Both sense and anti-sense RNA
  4. A particular hormone
AIPMT 2012 (Mains)
4

The first clinical gene therapy was given for treating

  1. Rheumatoid arthritis
  2. Adenosine deaminase deficiency
  3. Diabetes mellitus
  4. Chicken pox
AIPMT 2012 (Mains)
5

A single strand of nucleic acid tagged with a radioactive molecule is called

  1. Probe
  2. Selectable marker
  3. Vector
  4. Plasmid
AIPMT 2012 (Prelims)
6

Consumption of which one of the following foods can prevent the kind of blindness associated with vitamin 'A' deficiency?

  1. Flavr Savr tomato
  2. Canola
  3. Bt-brinjal
  4. Golden rice
AIPMT 2012 (Prelims)
7

Bacillus thuringiensis forms protein crystals which contain insecticidal protein. This protein:

  1. is activated by acid pH of the foregut of the insect pest.
  2. binds with epithelial cells of midgut of the insect pest ultimately killing it
  3. is coded by several genes including the gene cry
  4. does not kill the carrier bacterium which is itself resistant to this toxin
AIPMT 2011 (Mains)
8

Silencing of mRNA has been used in producing transgenic plants resistant to:

  1. White rusts
  2. Nematodes
  3. Bacterial blights
  4. Bollworms
AIPMT 2011 (Mains)
9

Maximum number of existing transgenic animals is of :

  1. Mice
  2. Cow
  3. Pig
  4. Fish
AIPMT 2011 (Prelims)
10

The process of RNA interference has been used in the development of plants resistant to :

  1. Nematodes
  2. Fungi
  3. Viruses
  4. Insects
AIPMT 2011 (Prelims)
11

Which one of the following is now being commercially produced by biotechnological procedures?

  1. Insulin
  2. Morphine
  3. Nicotine
  4. Quinine
AIPMT 2010 (Mains)

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