Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). In the light of the above statements, choose the most appropriate answer from the options given below
- (A) is not correct but (R) is correct
- Both (A) and (R) are correct and (R) is the correct explanation of (A)
- Both (A) and (R) are correct but (R) is not the correct explanation of (A)
- (A) is correct but (R) is not correct
Answer
(3) Both (A) and (R) are correct but (R) is not the correct explanation of (A)
Solution
Assertion: Correct – FSH is a glycoprotein hormone; as per NCERT, hormones which interact with membrane-bound receptors normally do not enter the target cell.
Reason: Correct – binding of FSH to its receptor generates second messengers (cyclic AMP), which in turn regulate cellular metabolism.
The reason why FSH does not enter the cell is its large, water-soluble protein nature (it cannot cross the lipid bilayer); the Reason only describes how the signal is relayed after binding.
⇒ (R) does not explain (A).
Answer: (3)