The Adenosine deaminase deficiency results into
- Addison's disease
- Dysfunction of immune system
- Parkinson's disease
- Digestive disorder
Answer
(2) Dysfunction of immune system
Solution
As per NCERT, the first clinical gene therapy (1990) was given to a 4-year-old girl with adenosine deaminase (ADA) deficiency.
⇒ The enzyme ADA is crucial for the immune system to function; its deficiency is caused by deletion of the gene for ADA.
∴ ADA deficiency results in dysfunction of the immune system (severe combined immunodeficiency).
Answer: (2)