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Principles of Inheritance and Variation

Previous year questions with solutions · 2000 – 2026

168Questions
34Papers covered
8.91% ↑60.4%Weightage in 2026
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’26
Year-wise statistics questions · papers · average per paper · weightage
YearQuestionsPapersAvg / paperWeightage
2026924.58.91% ↑60.4%
20253135.56% ↓47.2%
2024122610.53% ↑32.6%
20235157.94% ↓13.4%
202212269.16% ↑174.8%
20212123.33% ↓58.3%
20204148.00% ↓15.2%
20195159.43% ↑29.7%
20184147.27% ↓17.1%
20175158.77% ↑12.1%
2016924.57.83% ↑42.2%
20156235.50% ↓23.6%
20138247.21% ↑48.5%
2012522.54.85% ↑16.5%
20114224.17% ↓58.3%
2010924.510.00% ↑40%
20094147.14% ↑96.4%
20082123.64% ↓62.9%
20075159.80% ↓35.7%
200691915.25% ↑20.1%
200581812.70% ↓12.7%
200481814.55% ↑12.7%
200381812.90% ↑3.2%
200281812.50% ↓18.1%
200191915.25% ↑64.7%
20005159.26%

⚠ 1 of these questions are out of the current syllabus (marked on the question).

168 questions · newest paper first · page 6 of 6

151

A diseased man marries a normal woman. They get three daughters and five sons. All the daughters were diseased and sons were normal. The gene of this disease is : -

  1. Sex linked dominant
  2. Autosomal dominant
  3. Sex linked recessive
  4. Sex limited character
AIPMT 2002
152

Which of the following is a correct match -

  1. Sickle cell anaemia = X – Chromosome
  2. Down Syndrome = 21st Chromosome
  3. Haemophilia = Y – Chromosome
  4. Parkinson Disease = X & Y Chromosome
AIPMT 2002
153

Change in sequence of nucleotide in DNA is called as -

  1. Recombination
  2. Mutation
  3. Mutagen
  4. Translation
AIPMT 2002
154

If a diploid cell is treated with colchicine then it becomes : -

  1. Tetraploid
  2. Monoploid
  3. Diploid
  4. Triploid
AIPMT 2002
155

Two non-allelic genes produce the new phenotype when present together but fail to do so independently then it is called

  1. Polygene
  2. Complementary gene
  3. Non-complementary gene
  4. Epistasis
AIPMT 2001
156

A and B genes are linked. What shall be genotype of progeny in a cross between AB/ab and ab/ab?

  1. AABB and aabb
  2. None
  3. AaBb and aabb
  4. AAbb and aabb
AIPMT 2001
157

When dominant and recessive alleles express themselves together it is called

  1. Dominance
  2. Pseudo dominance
  3. Co-dominance
  4. Amphidominance
AIPMT 2001
158

Ratio of complementary genes is

  1. 9 : 3 : 4
  2. 9 : 7
  3. 12 : 3 : 1
  4. 9 : 3 : 3 : 4
AIPMT 2001
159

Independent assortment of genes does not take place when

  1. Genes are located on non-homologous chromosomes
  2. Genes are linked and located on same chromosome
  3. Genes are located on homologous chromosomes
  4. All the above
AIPMT 2001
160

Sickle cell anaemia is due to

  1. Change of amino acid in either or chain of haemoglobin
  2. Change of amino acid in chain of haemoglobin
  3. Change of amino acid in both and chain of haemoglobin
  4. Change of amino acid in chain of haemoglobin
AIPMT 2001
161

Number of Barr bodies in XXXX female is

  1. 3
  2. 1
  3. 2
  4. 4
AIPMT 2001
162

Male XX and female XY sometime occur due to

  1. Aneuploidy
  2. Deletion
  3. Transfer of segments in X and Y chromosomes
  4. Hormonal imbalance
AIPMT 2001
163

Probability of four sons to a couple is : -

  1. 116
  2. 18
  3. 14
  4. 132
AIPMT 2001
164

Due to the cross between TTRr × ttrr the resultant progenies showed how many percent plants tall, red flowered:

  1. 50%
  2. 100%
  3. 75%
  4. 25%
AIPMT 2000
165

According to mendelism which character is showing dominance?

  1. Green colour in seed coat
  2. Wrinkled seed
  3. Terminal position of flower
  4. Green pod colour
AIPMT 2000
166

Mongolian idiots are due to trisomy in 21st chromosome is called:

  1. Klinefelter's syndrome
  2. Down's syndrome
  3. Turner's syndrome
  4. Triplex syndrome
AIPMT 2000
167

Erythroblastosis foetalis is caused when:

  1. Rh- female & Rh+ male
  2. Rh- female & Rh- male
  3. Rh+ female & Rh+ male
  4. Rh+ female & Rh- male
AIPMT 2000
168

In Drosophila the XXY condition leads to femaleness whereas in human beings the same condition leads to Klinefelter's syndrome in male. It proves:

  1. Y chromosome is active in sex determination in both human beings and Drosophila
  2. In Drosophila Y-chromosome decides femaleness
  3. Y chromosome of man have genes for syndrome
  4. In human beings Y chromosome is active in sex determination
AIPMT 2000