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Principles of Inheritance and Variation

Previous year questions with solutions · 2000 – 2026

168Questions
34Papers covered
8.91% ↑60.4%Weightage in 2026
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’01
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’26
Year-wise statistics questions · papers · average per paper · weightage
YearQuestionsPapersAvg / paperWeightage
2026924.58.91% ↑60.4%
20253135.56% ↓47.2%
2024122610.53% ↑32.6%
20235157.94% ↓13.4%
202212269.16% ↑174.8%
20212123.33% ↓58.3%
20204148.00% ↓15.2%
20195159.43% ↑29.7%
20184147.27% ↓17.1%
20175158.77% ↑12.1%
2016924.57.83% ↑42.2%
20156235.50% ↓23.6%
20138247.21% ↑48.5%
2012522.54.85% ↑16.5%
20114224.17% ↓58.3%
2010924.510.00% ↑40%
20094147.14% ↑96.4%
20082123.64% ↓62.9%
20075159.80% ↓35.7%
200691915.25% ↑20.1%
200581812.70% ↓12.7%
200481814.55% ↑12.7%
200381812.90% ↑3.2%
200281812.50% ↓18.1%
200191915.25% ↑64.7%
20005159.26%

⚠ 1 of these questions are out of the current syllabus (marked on the question).

168 questions · newest paper first · page 3 of 6

61

Among the following characters, which one was not considered by Mendel in his experiments on pea?

  1. Stem-Tall or dwarf
  2. Pod-Inflated or constricted
  3. Trichomes-Glandular or non-glandular
  4. Seed-Green or yellow
NEET 2017
62

A cell at telophase stage is observed by a student in a plant brought from the field. He tells his teacher that this cell is not like other cells at telophase stage. There is no formation of cell plate and thus the cell is containing more number of chromosomes as compared to other dividing cells. This would result in -

  1. Polyteny
  2. Aneuploidy
  3. Polyploidy
  4. Somaclonal variation
NEET 2016 (Phase 1)
63

Pick out the correct statements :

  1. A, B and C only
  2. A, C and D only
  3. A and D only
  4. B and D only
NEET 2016 (Phase 1)
64

A tall true breeding garden pea plant is crossed with a dwarf true breeding garden pea plant. When the F1 plants were selfed the resulting genotypes were in the ratio of -

  1. 3 : 1 :: Tall : Dwarf
  2. 1 : 2 : 1 :: Tall heterozygous : Tall homozygous : Dwarf
  3. 1 : 2 : 1 :: Tall homozygous : Tall heterozygous : Dwarf
  4. 3 : 1 :: Dwarf : Tall
NEET 2016 (Phase 1)
65

Match the terms in Column-I with their description in Column-II and choose the correct option :

  1. (a)-(ii), (b)-(iii), (c)-(iv), (d)-(i)
  2. (a)-(iv), (b)-(i), (c)-(ii), (d)-(iii)
  3. (a)-(ii), (b)-(ii), (c)-(iv), (d)-(iii)
  4. (a)-(iv), (b)-(iii), (c)-(i), (d)-(ii)
NEET 2016 (Phase 1)
66

In a testcross involving F1 dihybrid flies, more parental-type offspring were produced than the recombinant-type offspring. This indicates

  1. Both of the characters are controlled by more than one gene
  2. The two genes are linked and present on the same chromosome
  3. The two genes are located on two different chromosomes
  4. Chromosomes failed to separate during meiosis
NEET 2016 (Phase 1)
67

Which of the following most appropriately describes haemophilia ?

  1. Chromosomal disorder
  2. X-linked recessive gene disorder
  3. Dominant gene disorder
  4. Recessive gene disorder
NEET 2016 (Phase 1)
68

The mechanism that causes a gene to move from one linkage group to another is called

  1. crossing-over
  2. translocation
  3. duplication
  4. inversion
NEET 2016 (Phase 2)
69

If a colour-blind man marries a woman who is homozygous for normal colour vision, the probability of their son being colour-blind is

  1. 0.75
  2. 0.5
  3. 0
  4. 1
NEET 2016 (Phase 2)
70

A true breeding plant is -

  1. produced due to cross-pollination among unrelated plants
  2. one that is able to breed on its own
  3. near homozygous and produces offspring of its own kind
  4. always homozygous recessive in its genetic constitution
Out of syllabusNEET 2016 (Phase 2)
71

The movement of a gene from one linkage group to another is called

  1. inversion
  2. translocation
  3. duplication
  4. crossing over
AIPMT 2015 (Cancelled)
72

Alleles are

  1. true breeding homozygotes
  2. different phenotype
  3. heterozygotes
  4. different molecular forms of a gene
AIPMT 2015 (Cancelled)
73

Multiple alleles are present

  1. on different chromosomes
  2. at the same locus of the chromosome
  3. at different loci on the same chromosome.
  4. on non-sister chromatids
AIPMT 2015 (Cancelled)
74

A man with blood group ‘A’ marries a woman with blood group ‘B’. What are all the possible blood groups of their offsprings?

  1. A and B only
  2. A, B, AB and O
  3. A, B and AB only
  4. O only
AIPMT 2015 (Cancelled)
75

How many pairs of contrasting characters in pea plants were studied by Mendel in his experiments?

  1. Eight
  2. Five
  3. Seven
  4. Six
AIPMT 2015 (Cancelled)
76

An abnormal human baby with ‘XXX’ sex chromosomes was born due to

  1. formation of abnormal sperms in the father
  2. fusion of two ova and one sperm
  3. formation of abnormal ova in the mother
  4. fusion of two sperms and one ovum
AIPMT 2015 (Cancelled)
77

Select the incorrect statement with regard to Haemophilia :

  1. It is a dominant disease
  2. A single protein involved in the clotting of blood is affected
  3. It is a recessive disease
  4. It is a sex-linked disease
NEET 2013
78

If both parents are carriers for thalassemia, which is an autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child ?

  1. 100%
  2. 25%
  3. no chance
  4. 50%
NEET 2013
79

If two persons with 'AB' blood group marry and have sufficiently large number of children, these children could be classified as 'A' blood group : 'AB' blood group : 'B' blood group in 1 : 2 : 1 ratio. Modern technique of protein electrophoresis reveals presence of both 'A' and 'B' type proteins in 'AB' blood group individuals. This is an example of :

  1. Codominance
  2. Partial dominance
  3. Incomplete dominance
  4. Complete dominance
NEET 2013
80

Which idea is depicted by a cross in which the F1 generation resembles both the parents?

  1. law of dominance
  2. co-dominance
  3. incomplete dominance
  4. inheritance of one gene
NEET 2013
81

Which of the following statements is not true of two genes that show 50% recombination frequency ?

  1. The genes are tightly linked
  2. The genes show independent assortment
  3. If the genes are present on the same chromosome, they undergo more than one crossovers in every meiosis.
  4. The genes may be on different chromosomes
NEET 2013
82

In our society women are blamed for producing female children. Choose the correct answer for the sex-determination in humans.

  1. Due to some defect like aspermia in man
  2. Due to the genetic make up of the particular sperm which fertilizes the egg
  3. Due to the genetic make up of the egg
  4. Due to some defect in the women
NEET 2013 (Karnataka)
83

Which one is the incorrect statement with regards to the importance of pedigree analysis?

  1. It confirms that DNA is the carrier of genetic information
  2. It helps to trace the inheritance of a specific trait
  3. It confirms that the trait is linked to one of the autosome
  4. It helps to understand whether the trait in question is dominant or recessive
NEET 2013 (Karnataka)
84

Down's syndrome in humans is due to :

  1. Three 'X' chromosomes
  2. Monosomy
  3. Three copies of chromosome 21
  4. Two 'Y' chromosomes
NEET 2013 (Karnataka)
85

Represented below is the inheritance pattern of a certain type of traits in humans. Which one of the following conditions could be an example of this pattern ? [figure]

  1. Haemophilia
  2. Sickle cell anaemia
  3. Thalassemia
  4. Phenylketonuria
AIPMT 2012 (Mains)
86

A test cross is carried out to :

  1. Determine whether two species or varieties will breed successfully
  2. Determine the genotype of a plant at F2
  3. Predict whether two traits are linked
  4. Assess the number of alleles of a gene
AIPMT 2012 (Mains)
87

Which one of the following is a wrong statement regarding mutations ?

  1. UV and gamma rays are mutagens
  2. Deletion and insertion of base pairs cause frame-shift mutations
  3. Cancer cells commonly show chromosomal aberrations
  4. Change in a single base pair of DNA does not cause mutation
AIPMT 2012 (Mains)
88

A normal-visioned man whose father was colour-blind, marries a woman whose father was also colour-blind. They have their first child as a daughter. What are the chances that this child would be colour-blind ?

  1. 50%
  2. 25%
  3. 100%
  4. Zero percent
AIPMT 2012 (Prelims)
89

F2 generation in a Mendelian cross showed that both genotypic and phenotypic ratios are same as 1 : 2 : 1. It represents a case of

  1. Monohybrid cross with incomplete dominance
  2. Co-dominance
  3. Monohybrid cross with complete dominance
  4. Dihybrid cross
AIPMT 2012 (Prelims)
90

Which one of the following conditions of the zygotic cell would lead to the birth of a normal human female child?

  1. only one Y chromosome
  2. only one X chromosome
  3. one X and one Y chromosome
  4. two X chromosomes
AIPMT 2011 (Mains)