Principles of Inheritance and Variation
Previous year questions with solutions · 2000 – 2026
168 Questions
34 Papers covered
8.91% ↑60.4% Weightage in 2026
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Year-wise statistics questions · papers · average per paper · weightage Year Questions Papers Avg / paper Weightage 2026 9 2 4.5 8.91% ↑60.4% 2025 3 1 3 5.56% ↓47.2% 2024 12 2 6 10.53% ↑32.6% 2023 5 1 5 7.94% ↓13.4% 2022 12 2 6 9.16% ↑174.8% 2021 2 1 2 3.33% ↓58.3% 2020 4 1 4 8.00% ↓15.2% 2019 5 1 5 9.43% ↑29.7% 2018 4 1 4 7.27% ↓17.1% 2017 5 1 5 8.77% ↑12.1% 2016 9 2 4.5 7.83% ↑42.2% 2015 6 2 3 5.50% ↓23.6% 2013 8 2 4 7.21% ↑48.5% 2012 5 2 2.5 4.85% ↑16.5% 2011 4 2 2 4.17% ↓58.3% 2010 9 2 4.5 10.00% ↑40% 2009 4 1 4 7.14% ↑96.4% 2008 2 1 2 3.64% ↓62.9% 2007 5 1 5 9.80% ↓35.7% 2006 9 1 9 15.25% ↑20.1% 2005 8 1 8 12.70% ↓12.7% 2004 8 1 8 14.55% ↑12.7% 2003 8 1 8 12.90% ↑3.2% 2002 8 1 8 12.50% ↓18.1% 2001 9 1 9 15.25% ↑64.7% 2000 5 1 5 9.26%
All 168 MCQ 163 Matching 5
TopicAll Chromosomal Theory of Inheritance, Linkage and Recombination Dihybrid Cross and Law of Independent Assortment Genetic Disorders: Chromosomal (Down's, Klinefelter's, Turner's) Genetic Disorders: Mendelian (Haemophilia, Colour Blindness, Sickle Cell, PKU, Thalassemia) Incomplete Dominance, Co-dominance and Multiple Allelism (ABO Blood Groups) Mendel's Laws of Inheritance, Monohybrid Cross Mutation Pedigree Analysis Polygenic Inheritance and Pleiotropy Sex Determination (Humans, Birds, Honey Bee, Grasshopper) YearAll 2026 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000
⚠ 1 of these questions are out of the current syllabus (marked on the question).
61
Among the following characters, which one was not considered by Mendel in his experiments on pea?
Stem-Tall or dwarf Pod-Inflated or constricted Trichomes-Glandular or non-glandular Seed-Green or yellow
NEET 2017
62
A cell at telophase stage is observed by a student in a plant brought from the field. He tells his teacher that this cell is not like other cells at telophase stage. There is no formation of cell plate and thus the cell is containing more number of chromosomes as compared to other dividing cells. This would result in -
Polyteny Aneuploidy Polyploidy Somaclonal variation
NEET 2016 (Phase 1)
63
Pick out the correct statements :
A, B and C only A, C and D only A and D only B and D only
NEET 2016 (Phase 1)
64
A tall true breeding garden pea plant is crossed with a dwarf true breeding garden pea plant. When the F1 plants were selfed the resulting genotypes were in the ratio of -
3 : 1 :: Tall : Dwarf 1 : 2 : 1 :: Tall heterozygous : Tall homozygous : Dwarf 1 : 2 : 1 :: Tall homozygous : Tall heterozygous : Dwarf 3 : 1 :: Dwarf : Tall
NEET 2016 (Phase 1)
65
Match the terms in Column-I with their description in Column-II and choose the correct option :
(a)-(ii), (b)-(iii), (c)-(iv), (d)-(i) (a)-(iv), (b)-(i), (c)-(ii), (d)-(iii) (a)-(ii), (b)-(ii), (c)-(iv), (d)-(iii) (a)-(iv), (b)-(iii), (c)-(i), (d)-(ii)
NEET 2016 (Phase 1)
66
In a testcross involving F1 dihybrid flies, more parental-type offspring were produced than the recombinant-type offspring. This indicates
Both of the characters are controlled by more than one gene The two genes are linked and present on the same chromosome The two genes are located on two different chromosomes Chromosomes failed to separate during meiosis
NEET 2016 (Phase 1)
67
Which of the following most appropriately describes haemophilia ?
Chromosomal disorder X-linked recessive gene disorder Dominant gene disorder Recessive gene disorder
NEET 2016 (Phase 1)
68
The mechanism that causes a gene to move from one linkage group to another is called
crossing-over translocation duplication inversion
NEET 2016 (Phase 2)
69
If a colour-blind man marries a woman who is homozygous for normal colour vision, the probability of their son being colour-blind is
0.75 0.5 0 1
NEET 2016 (Phase 2)
70
A true breeding plant is -
produced due to cross-pollination among unrelated plants one that is able to breed on its own near homozygous and produces offspring of its own kind always homozygous recessive in its genetic constitution
Out of syllabus NEET 2016 (Phase 2)
71
The movement of a gene from one linkage group to another is called
inversion translocation duplication crossing over
AIPMT 2015 (Cancelled)
72
Alleles are
true breeding homozygotes different phenotype heterozygotes different molecular forms of a gene
AIPMT 2015 (Cancelled)
73
Multiple alleles are present
on different chromosomes at the same locus of the chromosome at different loci on the same chromosome. on non-sister chromatids
AIPMT 2015 (Cancelled)
74
A man with blood group ‘A’ marries a woman with blood group ‘B’. What are all the possible blood groups of their offsprings?
A and B only A, B, AB and O A, B and AB only O only
AIPMT 2015 (Cancelled)
75
How many pairs of contrasting characters in pea plants were studied by Mendel in his experiments?
Eight Five Seven Six
AIPMT 2015 (Cancelled)
76
An abnormal human baby with ‘XXX’ sex chromosomes was born due to
formation of abnormal sperms in the father fusion of two ova and one sperm formation of abnormal ova in the mother fusion of two sperms and one ovum
AIPMT 2015 (Cancelled)
77
Select the incorrect statement with regard to Haemophilia :
It is a dominant disease A single protein involved in the clotting of blood is affected It is a recessive disease It is a sex-linked disease
NEET 2013
78
If both parents are carriers for thalassemia, which is an autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child ?
100% 25% no chance 50%
NEET 2013
79
If two persons with 'AB' blood group marry and have sufficiently large number of children, these children could be classified as 'A' blood group : 'AB' blood group : 'B' blood group in 1 : 2 : 1 ratio. Modern technique of protein electrophoresis reveals presence of both 'A' and 'B' type proteins in 'AB' blood group individuals. This is an example of :
Codominance Partial dominance Incomplete dominance Complete dominance
NEET 2013
80
Which idea is depicted by a cross in which the F1 generation resembles both the parents?
law of dominance co-dominance incomplete dominance inheritance of one gene
NEET 2013
81
Which of the following statements is not true of two genes that show 50% recombination frequency ?
The genes are tightly linked The genes show independent assortment If the genes are present on the same chromosome, they undergo more than one crossovers in every meiosis. The genes may be on different chromosomes
NEET 2013
82
In our society women are blamed for producing female children. Choose the correct answer for the sex-determination in humans.
Due to some defect like aspermia in man Due to the genetic make up of the particular sperm which fertilizes the egg Due to the genetic make up of the egg Due to some defect in the women
NEET 2013 (Karnataka)
83
Which one is the incorrect statement with regards to the importance of pedigree analysis?
It confirms that DNA is the carrier of genetic information It helps to trace the inheritance of a specific trait It confirms that the trait is linked to one of the autosome It helps to understand whether the trait in question is dominant or recessive
NEET 2013 (Karnataka)
84
Down's syndrome in humans is due to :
Three 'X' chromosomes Monosomy Three copies of chromosome 21 Two 'Y' chromosomes
NEET 2013 (Karnataka)
85
Represented below is the inheritance pattern of a certain type of traits in humans. Which one of the following conditions could be an example of this pattern ? [figure]
Haemophilia Sickle cell anaemia Thalassemia Phenylketonuria
AIPMT 2012 (Mains)
86
A test cross is carried out to :
Determine whether two species or varieties will breed successfully Determine the genotype of a plant at F2 Predict whether two traits are linked Assess the number of alleles of a gene
AIPMT 2012 (Mains)
87
Which one of the following is a wrong statement regarding mutations ?
UV and gamma rays are mutagens Deletion and insertion of base pairs cause frame-shift mutations Cancer cells commonly show chromosomal aberrations Change in a single base pair of DNA does not cause mutation
AIPMT 2012 (Mains)
88
A normal-visioned man whose father was colour-blind, marries a woman whose father was also colour-blind. They have their first child as a daughter. What are the chances that this child would be colour-blind ?
50% 25% 100% Zero percent
AIPMT 2012 (Prelims)
89
F2 generation in a Mendelian cross showed that both genotypic and phenotypic ratios are same as 1 : 2 : 1. It represents a case of
Monohybrid cross with incomplete dominance Co-dominance Monohybrid cross with complete dominance Dihybrid cross
AIPMT 2012 (Prelims)
90
Which one of the following conditions of the zygotic cell would lead to the birth of a normal human female child?
only one Y chromosome only one X chromosome one X and one Y chromosome two X chromosomes
AIPMT 2011 (Mains)