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Biotechnology and its Applications · Question 38

NEET 2016 (Phase 2)MCQEasy📈 Topic in 12% papers+4−1
1

Which kind of therapy was given in 1990 to a four-year-old girl with adenosine deaminase [ADA] deficiency ?

  1. Radiation therapy
  2. Immunotherapy
  3. Gene therapy
  4. Chemotherapy

Answer

(3) Gene therapy

Solution

As per NCERT, the first clinical gene therapy was given in 1990 to a 4-year old girl with adenosine deaminase (ADA) deficiency.

⇒ Lymphocytes from the patient's blood were grown in culture, a functional ADA cDNA was introduced into them using a retroviral vector, and the cells were returned to the patient.

Answer: (3)

NEET 2016 (Phase 2)

Keep practising — Biotechnology and its Applications

2

Golden rice is a genetically modified crop plant where the incorporated gene is meant for biosynthesis of -

  1. Vitamin C
  2. Omega 3
  3. Vitamin A
  4. Vitamin B
AIPMT 2015
3

In Bt cotton, the Bt toxin present in plant tissue as pro-toxin is converted into active toxin due to :

  1. action of gut micro-organisms
  2. presence of conversion factors in insect gut
  3. alkaline pH of the insect gut
  4. acidic pH of the insect gut
AIPMT 2015 (Cancelled)
4

Which body of the Government of India regulates GM research and safety of introducing GM organisms for public services ?

  1. Research Committee on Genetic Manipulation
  2. Genetic Engineering Approval Committee
  3. Indian Council of Agricultural Research
  4. Bio-safety committee
AIPMT 2015 (Cancelled)
5

The crops engineered for glyphosate are resistant/tolerant to :

  1. Bacteria
  2. Herbicides
  3. Fungi
  4. Insects
AIPMT 2015 (Cancelled)
6

The first human hormone produced by recombinant DNA technology is :

  1. Estrogen
  2. Insulin
  3. Thyroxin
  4. Progesterone
AIPMT 2014
7

Which of the following Bt crops is being grown in India by the farmers ?

  1. Soybean
  2. Cotton
  3. Brinjal
  4. Maize
NEET 2013
8

RNA interference involves :-

  1. Interference of RNA in synthesis of DNA
  2. Synthesis of cDNA from RNA using reverse transcriptase
  3. Synthesis of mRNA from DNA
  4. Silencing of specific mRNA due to complementary RNA
NEET 2013 (Karnataka)
9

Which one of the following vectors is used to replace the defective gene in gene therapy ?

  1. Ti plasmid
  2. Cosmid
  3. Ri plasmid
  4. Adenovirus
NEET 2013 (Karnataka)
10

Tobacco plants resistant to a nematode have been developed by the introduction of DNA that produced (in the host cells) :

  1. An antifeedant
  2. A toxic protein
  3. Both sense and anti-sense RNA
  4. A particular hormone
AIPMT 2012 (Mains)
11

The first clinical gene therapy was given for treating

  1. Rheumatoid arthritis
  2. Adenosine deaminase deficiency
  3. Diabetes mellitus
  4. Chicken pox
AIPMT 2012 (Mains)

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